Neural Regeneration Research
www.nrronline.org
2021 Volume 16 April Number 4
综述
The use of hydrogel-delivered extracellular vesicles in recovery of motor function in stroke: a testable experimental hypothesis for clinical translation including behavioral and neuroimaging assessment approaches
水凝胶递送的细胞外囊泡在中风后功能恢复中的应用：行为和神经影像学评估方法的临床转化实验假设
Magdalini Tsintou, Kyriakos Dalamagkas, Tara L Moore, Yogesh Rathi, Marek Kubicki, Douglas L Rosene, Nikos Makris | Massachusetts General Hospital, Harvard Medical School, USA
MicroRNAs in laser-induced choroidal neovascularization in mice and rats: their expression and potential therapeutic targets
MicroRNAs在激光诱导小鼠和大鼠脉络膜新生血管中的表达及其潜在治疗靶点
Bridget Martinez, Philip V. Peplow | University of Otago,New Zealand
Advances in human stem cell therapies: pre-clinical studies and the outlook for central nervous system regeneration
干细胞疗法的进展和中枢神经系统再生的前景
Lindsey H. Forbes, Melissa R. Andrews | University of Southampton, UK
The phenotypic convergence between microglia and peripheral macrophages during development and neuroinflammation paves the way for new therapeutic perspectives
小胶质细胞和外周巨噬细胞在发育和神经炎症过程中的表型趋同为新的治疗前景铺平了道路
Francesca Grassivaro, Gianvito Martino, Cinthia Farina | San Raffaele Scientific Institute, Italy
Efficacy of the epothilones in central nervous system trauma treatment: what’s age got to do with it?
埃博霉素在中枢神经系统创伤治疗中的功效：与年龄有关？
Jayden Clark, Zhendan Zhu, Jyoti Chuckowree, Tracey Dickson, Catherine Blizzard | University of Tasmania, Australia
Modeling subcortical ischemic white matter injury in rodents: unmet need for a breakthrough in translational research
啮齿动物的皮质下缺血性白质损伤建模：未满足转化研究突破的需求
Yuexian Cui, Xuelian Jin, Jun Young Choi, Byung Gon Kim | Ajou University School of Medicine, Republic of Korea
Deciphering the dual role and prognostic potential of PINK1 across cancer types
神经退行性病中的PINK1：理解双刃剑
Katherine Dai, Daniel P. Radin, Donna Leonardi | Yale University, USA
The emerging role of probiotics in neurodegenerative diseases: new hope for Parkinson’s disease?
益生菌在神经退行性疾病中的新兴作用：帕金森病的新希望？
Vanessa Castelli, Michele d’Angelo, Massimiliano Quintiliani, Elisabetta Benedetti, Maria Grazia Cifone, Annamaria Cimini | University of L’Aquila, Italy
Hippo signaling: bridging the gap between cancer and neurodegenerative disorders
Hippo信号: 弥合癌症与神经退行性疾病之间的鸿沟
Neha Gogia, Anuradha Venkatakrishnan Chimata, Prajakta Deshpande, Aditi Singh, Amit Singh | University of Dayton, USA
Nerve growth factor in muscle afferent neurons of peripheral artery disease and autonomic function
周围动脉疾病肌肉传入神经元中的神经生长因子与自主神经功能
Lu Qin, Jianhua Li | Penn State University College of Medicine, USA
Transcranial direct current stimulation for auditory verbal hallucinations: a systematic review of clinical trials
经颅直流电刺激治疗听觉言语幻觉的系统评价
Samaneh Rashidi, Myles Jones, Eric Murillo-Rodriguez, Sergio Machado, Youguo Hao, Ali Yadollahpour | University of Sheffield, UK
观点
Prevention and treatment of cerebral palsy with cord blood stem cells and cord-derived mesenchymal stem cells
预防和治疗脑瘫的再生医学
Haruo Shintaku | Osaka City University Graduate School of Medicine, Japan
Mitochondrial integrity in neuronal injury and repair
神经元损伤和修复中线粒体的完整性
Qi Han, Xiao-Ming Xu | Indiana University School of Medicine, USA
Sox9 in the developing central nervous system – a jack of all trades?
发育中枢神经系统中的Sox9 –万事通？
Julia K. Vogel, Michael Wegner | Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany
Patterning inconsistencies restrict the true potential of dopaminergic neurons derived from human induced pluripotent stem cells
模式不一致限制了人类诱导的多能干细胞衍生的多巴胺能神经元的真正潜力
Sameehan Mahajani, Mathias Bähr, Sebastian Kügler | Stanford University School of Medicine, USA
Strategies to prevent and detect intraoperative spinal cord ischemia during complex aortic surgery: from drainages and biomarkers
预防和检测复杂主动脉手术期间术中脊髓缺血的策略：引流物和生物标志物
Alexander Gombert, Florian Simon | University Hospital RWTH Aachen, Germany
Stem cell-derived extracellular vesicles as potential mechanism for repair of microvascular damage within and outside of the central nervous system in amyotrophic lateral sclerosis: perspective schema
干细胞来源的细胞外囊泡是修复肌萎缩性侧索硬化的中枢神经系统内外微血管损伤的潜在机制：观点
Svitlana Garbuzova-Davis, Cesario V. Borlongan | University of South Florida, USA
The important functional role of TDP-43 plays in amyotrophic lateral sclerosis-frontotemporal dementia
TDP-43在神经退行性疾病中起重要作用
Liam Chen | Johns Hopkins University School of Medicine, USA
Impact of the metabolic syndrome on the evolution of neurodegenerative diseases
代谢综合征对神经退行性疾病演变的影响
Ana Paula de A. Boleti, Jeeser Alves Almeida, Ludovico Migliolo | Universidade Católica Dom Bosco, Brazil
Regulation of Parkin-dependent mitophagy by Bcl-2-associated athanogene (BAG) family members
Bcl-2-相关的致癌基因家庭成员对帕金依赖性线粒体的调节
Minesh Kapadia, Mitchell L. De Snoo, Lorraine V. Kalia, Suneil K. Kalia | University of Toronto, Canada
Mitochondrial bioenergetics and neurodegeneration: a paso doble
线粒体生物能和神经退行性变：双步
Alice Rossi, Paola Pizzo | University of Padua, Italy
Analysis of corneal nerve plexus in corneal confocal microscopy images
角膜共聚焦显微镜图像分析角膜神经丛
Yu-Chi Liu, Molly Tzu-Yu Lin, Jodhbir S. Mehta | Singapore Eye Research Institute, Singapore
研究原著
脑损伤与神经再生
Lineage tracing of direct astrocyte-to-neuron conversion in the mouse cortex
小鼠皮质中星形胶质细胞向神经元直接转化的谱系追踪
Zongqin Xiang, Liang Xu, Minhui Liu, Qingsong Wang, Wen Li, Wenliang Lei, Gong Chen
Neurons derived from humaninduced pluripotent stem cells express mu and kappa opioid receptors
人源多能干细胞可诱导分化为Mu和Kappa阿片受体的神经元
Zhi-Hai Ju, Xuan Liang, Yao-Yao Ren, Luo-Wa Shu, Yan-Hong Yan, Xu Cui
Modeling protein-protein interactions in axon initial segment to understand their potential impact on action potential initiation
轴突起始段蛋白-蛋白相互作用潜在影响动作电位的启动
Piyush Bhardwaj, Don Kulasiri, Sandhya Samarasinghe
Batroxobin inhibits astrocyte activation following nigrostriatal pathway injury
抑制黑质纹状体通路损伤后星形胶质细胞活化的巴曲酶
Zhuo Zhang, Xue Bao, Dan Li
Abnormal Glu/mGluR2/3/PI3K pathway in the hippocampal neurovascular unit leads to diabetes-related depression
海马神经血管单元中Glu / mGluR2 / 3 / PI3K途径异常导致糖尿病相关性抑郁症
Jian Liu, Yuan-Shan Han, Lin Liu, Lin Tang, Hui Yang, Pan Meng, Hong-Qing Zhao, Yu-Hong Wang
Association between plasma immunoproteasome and 90-day prognosis after first-ever ischemic stroke
首次缺血性脑卒中后血浆免疫蛋白酶体与90d预后的关系
Xing-Yong Chen, Ming Fu, Shao-Fen Wan, Xu Zhang, Yin-Zhou Wang
Neuroimaging mechanisms of highfrequency repetitive transcranial
magnetic stimulation for treatment of amnestic mild cognitive impairment: a double-blind randomized sham-controlled trial高频重复经颅磁刺激治疗遗忘型轻度认知障碍的神经影像学机制:一项双盲随机假手术对照试验
Li-Qiong Yuan, Qing Zeng, Dan Wang, Xiu-Yun Wen, Yu Shi, Fen Zhu, Shang-Jie Chen, Guo-Zhi Huang
Comparison of cerebral activation between motor execution and motor imagery of self-feeding activity
执行自我进食活动行为与运动想象脑区激活的比较
Moemi Matsuo, Naoki Iso, Kengo Fujiwara, Takefumi Moriuchi, Daiki Matsuda, Wataru Mitsunaga, Akira Nakashima, Toshio Higashi
Altered electroencephalographic networks in developmental dyslexia after remedial training: a prospective case-control study
视觉语义任务训练后发育性阅读障碍患儿的脑电图网络变化：一项前瞻性病例对照研究
Juliana A. Dushanova, Stefan A. Tsokov
脊髓损伤与神经再生
Synaptic remodeling in mouse motor cortex after spinal cord injury
脊髓损伤小鼠大脑运动皮质突触的重塑
Ke-Xue Zhang, Jia-Jia Zhao, Wei Chai, Ji-Ying Chen
Exogenous platelet-derived growth factor improves neurovascular unit recovery after spinal cord injury
外源性血小板衍生生长因子恢复脊髓损伤后的神经血管单元
Lu-Xia Ye, Ning-Chen An, Peng Huang, Duo-Hui Li, Zhi-Long Zheng, Hao Ji, Hao Li, Da-Qing Chen, Yan-Qing Wu, Jian Xiao, Ke Xu, Xiao-Kun Li, Hong-Yu Zhang
LncRNA Airsci increases the inflammatory response after spinal cord injury in rats through the nuclear factor kappa B signaling pathway
长非编码RNA Airsci增强大鼠脊髓损伤后的炎症反应
Tao Zhang, Kang Li, Zi-Lu Zhang, Kai Gao, Chao-Liang Lv
神经退行性疾病与神经再生
Co-nanoencapsulated meloxicam and curcumin improves cognitive impairment induced by amyloidbeta through modulation of cyclooxygenase-2 in mice
美洛昔康与姜黄素共负载纳米胶囊可改善淀粉样β蛋白诱导的认知功能障碍
Maria Eduarda Ziani Gutierrez, Anne Suély Pinto Savall, Edina da Luz Abreu, Kelly Ayumi Nakama, Renata Bem Dos Santos, Marina Costa Monteiro Guedes, Daiana Silva Ávila, Cristiane Luchese, Sandra Elisa Haas, Caroline Brandão Quines, Simone Pinton
Melatonin ameliorates microvessel abnormalities in the cerebral cortex and hippocampus in a rat model of Alzheimer’s disease
褪黑素可改善阿尔茨海默病大脑皮质和海马中微血管的异常
Pan Wang, Hai-Juan Sui, Xiao-Jia Li, Li-Na Bai, Jing Bi, Hong Lai
Caveolin-1 downregulation promotes the dopaminergic neuron-like differentiation of human adipose-derived mesenchymal stem cells
下调窖蛋白1表达可促进人脂肪间充质干细胞向多巴胺能神经元样分化
Chao Han, Ya-Jun Wang, Ya-Chen Wang, Xin Guan, Liang Wang, Li-Ming Shen, Wei Zou, Jing Liu
Regulated upon activation, normal T cell expressed and secreted (RANTES) levels in the peripheral blood of patients with Alzheimer’s disease
阿尔茨海默病早期诊断标志物：外周血受激活调节正常T细胞表达和分泌因子
Gabriela Vacínová, Daniela Vejražkova, Robert Rusina, Iva Holmerová, Hana Vaňková, Eva Jarolímová, Josef Včelák, Běla Bendlová, Markéta Vaňková
